ロード中...

Wnt/β-catenin signaling and AXIN1 regulate apoptosis mediated by inhibition of BRAF(V600E) kinase in human melanoma

As the Wnt/β-catenin signaling pathway is linked to melanoma pathogenesis and to patient survival, we conducted a kinome siRNA screen in melanoma cells to expand our understanding of kinases that regulate this pathway, and to illuminate potential therapeutic directions. We found that BRAF signaling,...

詳細記述

保存先:
書誌詳細
主要な著者: Biechele, Travis L., Kulikauskas, Rima M., Toroni, Rachel A., Lucero, Olivia M., Swift, Reyna D., James, Richard G., Robin, Nick C., Dawson, David W., Moon, Randall T., Chien, Andy J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297477/
https://ncbi.nlm.nih.gov/pubmed/22234612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002274
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!