טוען...
Wnt/β-catenin signaling and AXIN1 regulate apoptosis mediated by inhibition of BRAF(V600E) kinase in human melanoma
As the Wnt/β-catenin signaling pathway is linked to melanoma pathogenesis and to patient survival, we conducted a kinome siRNA screen in melanoma cells to expand our understanding of kinases that regulate this pathway, and to illuminate potential therapeutic directions. We found that BRAF signaling,...
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| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297477/ https://ncbi.nlm.nih.gov/pubmed/22234612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002274 |
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