Activation of Wnt/β-Catenin Signaling Increases Apoptosis in Melanoma Cells Treated with Trail

While the TRAIL pathway represents a promising therapeutic target in melanoma, resistance to TRAIL-mediated apoptosis remains a barrier to its successful adoption. Since the Wnt/β-catenin pathway has been implicated in facilitating melanoma cell apoptosis, we investigated the effect of Wnt/β-catenin...

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Main Authors: Zimmerman, Zachary F., Kulikauskas, Rima M., Bomsztyk, Karol, Moon, Randall T., Chien, Andy J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711908/
https://ncbi.nlm.nih.gov/pubmed/23869245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069593
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