Carregant...
Regioselective Synthesis of Water Soluble Monophosphate Derivatives of Combretastatin A-1
The natural products combretastatin A-4 (CA4) and combretastatin A-1 (CA1) are potent cancer vascular disrupting agents (VDAs) and inhibitors of tubulin assembly (IC(50) = 1–2 μM). The phosphorylated prodrugs CA4P and CA1P are undergoing human clinical trials against cancer. CA1 is unique due to its...
Guardat en:
| Autors principals: | , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275140/ https://ncbi.nlm.nih.gov/pubmed/21718055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np200104t |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|