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Allosteric and Orthosteric Sites in CC Chemokine Receptor (CCR5), a Chimeric Receptor Approach

Chemokine receptors play a major role in immune system regulation and have consequently been targets for drug development leading to the discovery of several small molecule antagonists. Given the large size and predominantly extracellular receptor interaction of endogenous chemokines, small molecule...

詳細記述

保存先:
書誌詳細
主要な著者: Thiele, Stefanie, Steen, Anne, Jensen, Pia C., Mokrosinski, Jacek, Frimurer, Thomas M., Rosenkilde, Mette M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199500/
https://ncbi.nlm.nih.gov/pubmed/21878623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243808
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