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μ-Conotoxins that differentially block sodium channels Na(V)1.1 through 1.8 identify those responsible for action potentials in sciatic nerve

Voltage-gated sodium channels (VGSCs) are important for action potentials. There are seven major isoforms of the pore-forming and gate-bearing α-subunit (Na(V)1) of VGSCs in mammalian neurons, and a given neuron can express more than one isoform. Five of the neuronal isoforms, Na(V)1.1, 1.2, 1.3, 1....

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Xehetasun bibliografikoak
Egile Nagusiak: Wilson, Michael J., Yoshikami, Doju, Azam, Layla, Gajewiak, Joanna, Olivera, Baldomero M., Bulaj, Grzegorz, Zhang, Min-Min
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121861/
https://ncbi.nlm.nih.gov/pubmed/21652775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107027108
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