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μ-Conotoxins that differentially block sodium channels Na(V)1.1 through 1.8 identify those responsible for action potentials in sciatic nerve
Voltage-gated sodium channels (VGSCs) are important for action potentials. There are seven major isoforms of the pore-forming and gate-bearing α-subunit (Na(V)1) of VGSCs in mammalian neurons, and a given neuron can express more than one isoform. Five of the neuronal isoforms, Na(V)1.1, 1.2, 1.3, 1....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121861/ https://ncbi.nlm.nih.gov/pubmed/21652775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107027108 |
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