Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae.
Pneumolysin is the thiol-activated cytolysin produced by Streptococcus pneumoniae. Mice were immunized with a genetically engineered toxoid version of pneumolysin, which was derived from a serotype 2 pneumococcus. The toxoid carried the mutation Trp-433-->Phe. Alum was used as the adjuvant. Immunize...
محفوظ في:
| الحاوية / القاعدة: | Infect Immun |
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| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1994
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303321/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7960154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.12.5683-5688.1994 |
| الوسوم: |
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