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Effect of immunization with pneumolysin on survival time of mice challenged with Streptococcus pneumoniae.

The role of the cytolytic toxin pneumolysin in the pathogenicity of Streptococcus pneumoniae was investigated. Pneumolysin was purified to homogeneity and used to immunize mice. When these mice were subsequently challenged via the nasal route with virulent S. pneumoniae, they survived significantly...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Paton, J C, Lock, R A, Hansman, D J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1983
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC264890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6840851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.40.2.548-552.1983
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