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Effect of immunization with pneumolysin on survival time of mice challenged with Streptococcus pneumoniae.

The role of the cytolytic toxin pneumolysin in the pathogenicity of Streptococcus pneumoniae was investigated. Pneumolysin was purified to homogeneity and used to immunize mice. When these mice were subsequently challenged via the nasal route with virulent S. pneumoniae, they survived significantly...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Paton, J C, Lock, R A, Hansman, D J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1983
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC264890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6840851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.40.2.548-552.1983
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