Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells

The NF1 tumor suppressor gene encodes a GTPase-activating protein called neurofibromin that negatively regulates Ras signaling. Mutations in NF1 cause neurofibromatosis type 1 (NF1). The development of neurofibromas, which are complex tumors composed of multiple cell types, is a hallmark of NF1. Som...

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Bibliographic Details
Main Authors:	Feng-Chun, Yang, Ingram, David A., Chen, Shi, Hingtgen, Cynthia M., Ratner, Nancy, Monk, Kelly R., Clegg, Travis, White, Hilary, Mead, Laura, Wenning, Mary Jo, Williams, David A., Kapur, Reuben, Atkinson, Simon J., Clapp, D. Wade
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 2003
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC296994/ https://ncbi.nlm.nih.gov/pubmed/14679180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319195
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Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells

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