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Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans
Neurofibromatosis type 1 (NF1) results from mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. NF1 patients display diverse clinical manifestations, including vascular disease, which results from neointima formation and vessel occlusion. However, the pathogenesis of...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827964/ https://ncbi.nlm.nih.gov/pubmed/20160346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41443 |
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