Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans

Neurofibromatosis type 1 (NF1) results from mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. NF1 patients display diverse clinical manifestations, including vascular disease, which results from neointima formation and vessel occlusion. However, the pathogenesis of...

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Bibliografische gegevens
Hoofdauteurs: Lasater, Elisabeth A., Li, Fang, Bessler, Waylan K., Estes, Myka L., Vemula, Sasidhar, Hingtgen, Cynthia M., Dinauer, Mary C., Kapur, Reuben, Conway, Simon J., Ingram, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2010
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827964/
https://ncbi.nlm.nih.gov/pubmed/20160346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41443
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