Colon tumor cell growth inhibitory activity of sulindac sulfide and other NSAIDs is associated with PDE5 inhibition

In experimental studies, nonsteroidal anti-inflammatory drugs (NSAIDs) display promising antineoplastic activity, but toxicity resulting from cyclooxygenase (COX) inhibition limits their clinical use for chemoprevention. Studies suggest that the mechanism may be COX independent, although alternative...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tinsley, Heather N., Gary, Bernard D., Thaiparambil, Jose, Li, Nan, Lu, Wenyan, Li, Yonghe, Maxuitenko, Yulia Y., Keeton, Adam B., Piazza, Gary A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955813/
https://ncbi.nlm.nih.gov/pubmed/20876730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0030
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