Salinomycin suppresses LRP6 expression and inhibits both Wnt/β-catenin and mTORC1 signaling in breast and prostate cancer cells

Por Lu, Wenyan, Li, Yonghe
Publicado em 2014

Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells

Por Lu, Wenyan, Lin, Cuihong, Li, Yonghe
Publicado em 2014

Frizzled7 as an emerging target for cancer therapy

Por King, Taj D., Zhang, Wei, Suto, Mark J., Li, Yonghe
Publicado em 2011

Low-Density Lipoprotein Receptor-related Protein 1 Promotes Cancer Cell Migration and Invasion by Inducing the Expression of Matrix Metalloproteinase 2 and 9

Por Song, Heesang, Li, Yonghe, Lee, Jiyeon, Schwartz, Alan L., Bu, Guojun
Publicado em 2009

Discovery of novel frizzled-7 inhibitors by targeting the receptor’s transmembrane domain

Por Zhang, Wei, Lu, Wenyan, Ananthan, Subramaniam, Suto, Mark J., Li, Yonghe
Publicado no Oncotarget (2017)

Mesd Is a Universal Inhibitor of Wnt Co-receptor LRP5/6 and Blocks Wnt/β-catenin Signaling in Cancer Cells

Por Lu, Wenyan, Liu, Chia-Chen, Thottassery, Jaideep V., Bu, Guojun, Li, Yonghe
Publicado em 2010

Synthesis and preliminary assessment of the anticancer and Wnt/β-catenin inhibitory activity of small amide libraries of fenamates and profens

Por Mathew, Bini, Hobrath, Judith V., Lu, Wenyan, Li, Yonghe, Reynolds, Robert C.
Publicado no Med Chem Res (2017)

Identification of a Major Cyclic AMP-Dependent Protein Kinase A Phosphorylation Site within the Cytoplasmic Tail of the Low-Density Lipoprotein Receptor-Related Protein: Implicatio...

Por Li, Yonghe, van Kerkhof, Peter, Marzolo, Maria Paz, Strous, Ger J., Bu, Guojun
Publicado em 2001

Discovery of novel allosteric Eg5 inhibitors through structure-based virtual screening

Por Zhang, Wei, Zhai, Ling, Lu, Wenyan, Boohaker, Rebecca J., Padmalayam, Indira, Li, Yonghe
Publicado no Chem Biol Drug Des (2016)

Suppression of Wnt/β-catenin signaling inhibits prostate cancer cell proliferation

Por Lu, Wenyan, Tinsley, Heather N., Keeton, Adam, Qu, Zhican, Piazza, Gary A., Li, Yonghe
Publicado em 2008

Silibinin Inhibits Wnt/β-catenin Signaling by Suppressing Wnt Co-receptor LRP6 Expression in Human Prostate and Breast Cancer Cells

Por Lu, Wenyan, Lin, Cuihong, King, Taj D., Chen, Honghong, Reynolds, Robert C., Li, Yonghe
Publicado em 2012

Identification of quinazoline compounds as novel potent inhibitors of Wnt/β-catenin signaling in colorectal cancer cells

Por Li, Yonghe, Lu, Wenyan, Saini, Surendra K., Moukha-Chafiq, Omar, Pathak, Vibha, Ananthan, Subramaniam
Publicado no Oncotarget (2016)

Dkk1 Stabilizes Wnt Co-Receptor LRP6: Implication for Wnt Ligand-Induced LRP6 Down-Regulation

Por Li, Yonghe, Lu, Wenyan, King, Taj D., Liu, Chia-Chen, Bijur, Gautam N., Bu, Guojun
Publicado em 2010

Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway

Por Lu, Wenyan, Lin, Cuihong, Roberts, Michael J., Waud, William R., Piazza, Gary A., Li, Yonghe
Publicado em 2011

Multi-targeted therapy of cancer by niclosamide: a new application for an old drug

Por Li, Yonghe, Li, Pui Kai, Roberts, Michael J., Arend, Rebecca, Samant, Rajeev S., Buchsbaum, Donald J.
Publicado em 2014

Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation

Por Knisely, Jane M., Li, Yonghe, Griffith, Janice M., Geuze, Hans J., Schwartz, Alan L., Bu, Guojun
Publicado em 2007

Inhibition of PDE5 by sulindac sulfide selectively induces apoptosis and attenuates oncogenic Wnt/β-catenin mediated transcription in human breast tumor cells

Por Tinsley, Heather N., Gary, Bernard D., Keeton, Adam B., Lu, Wenyan, Li, Yonghe, Piazza, Gary A.
Publicado em 2011

Mesd Is A General Inhibitor of Different Wnt Ligands In Wnt/LRP Signaling and Inhibits PC-3 Tumor Growth In Vivo

Por Lin, Cuihong, Lu, Wenyan, Zhai, Ling, Bethea, Traci, Berry, Kristy, Qu, Zhican, Waud, William R., Li, Yonghe
Publicado em 2011

The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/β-Catenin Signaling in Cancer Cells

Por Lin, Cuihong, Lu, Wenyan, Zhang, Wei, Londoño-Joshi, Angelina I., Buchsbaum, Donald J., Bu, Guojun, Li, Yonghe
Publicado em 2013

Breast Cancer-derived Dickkopf1 Inhibits Osteoblast Differentiation and Osteoprotegerin Expression: Implication for Breast Cancer Osteolytic Bone Metastases

Por Bu, Guojun, Lu, Wenyan, Liu, Chia-Chen, Selander, Katri, Yoneda, Toshiyuki, Hall, Christopher, Keller, Evan T., Li, Yonghe
Publicado em 2008