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Breast Cancer-derived Dickkopf1 Inhibits Osteoblast Differentiation and Osteoprotegerin Expression: Implication for Breast Cancer Osteolytic Bone Metastases

Most breast cancer metastases in bone form osteolytic lesions, but the mechanisms of tumor-induced bone resorption and destruction are not fully understood. Although it is well recognized that Wnt/β-catenin signaling is important for breast cancer tumorigenesis, the role of this pathway in breast ca...

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Autori principali: Bu, Guojun, Lu, Wenyan, Liu, Chia-Chen, Selander, Katri, Yoneda, Toshiyuki, Hall, Christopher, Keller, Evan T., Li, Yonghe
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732167/
https://ncbi.nlm.nih.gov/pubmed/18546262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23625
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