Quantitative relationship between guanine O(6)-alkyl lesions produced by Onrigin(™) and tumor resistance by O(6)-alkylguanine-DNA alkyltransferase

類似資料

• Design of a Hypoxia-Activated Prodrug Inhibitor of O(6)-Alkylguanine-DNA Alkyltransferase
  著者:: Zhu, Rui, 等
  出版事項: (2012)
• A strategy for selective O(6)-alkylguanine-DNA alkyltransferase depletion under hypoxic conditions
  著者:: Penketh, Philip G., 等
  出版事項: (2012)
• Development of an O(6)-alkylguanine—DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-(3)H]O(6)-benzylguanine to the protein
  著者:: Ishiguro, Kimiko, 等
  出版事項: (2008)
• KS900: a hypoxia-directed, reductively activated methylating antitumor prodrug that selectively ablates O(6)-alkylguanine-DNA alkyltransferase in neoplastic cells
  著者:: Baumann, Raymond P., 等
  出版事項: (2011)
• 4-Nitrobenzyloxycarbonyl Derivatives of O(6)-Benzylguanine as Hypoxia-Activated Prodrug Inhibitors of O(6)-Alkylguanine-DNA Alkyltransferase (AGT) which Produces Resistance to Agents Targeting the O-6 Position of DNA Guanine
  著者:: Zhu, Rui, 等
  出版事項: (2011)