تحميل...
Development of an O(6)-alkylguanine—DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-(3)H]O(6)-benzylguanine to the protein
Although it is known that (i) O(6)-alkylguanine—DNA alkyltransferase (AGT) confers tumor cell resistance to guanine O(6)-targeting drugs such as cloretazine, carmustine, and temozolomide and that (ii) AGT levels in tumors are highly variable, measurement of AGT activity in tumors before treatment is...
محفوظ في:
| المؤلفون الرئيسيون: | , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
2008
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773450/ https://ncbi.nlm.nih.gov/pubmed/18783719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.08.009 |
| الوسوم: |
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