Hypoxia-selective O(6)-Alkylguanine-DNA Alkyltransferase Inhibitors: Design, Synthesis and Evaluation of 6-(Benzyloxy)-2-(aryldiazenyl)-9H-purines as Prodrugs of O(6)-Benzylguanine

অনুরূপ উপাদানগুলি

• Design of a Hypoxia-Activated Prodrug Inhibitor of O(6)-Alkylguanine-DNA Alkyltransferase
  অনুযায়ী: Zhu, Rui, অন্যান্য
  প্রকাশিত: (2012)
• 4-Nitrobenzyloxycarbonyl Derivatives of O(6)-Benzylguanine as Hypoxia-Activated Prodrug Inhibitors of O(6)-Alkylguanine-DNA Alkyltransferase (AGT) which Produces Resistance to Agents Targeting the O-6 Position of DNA Guanine
  অনুযায়ী: Zhu, Rui, অন্যান্য
  প্রকাশিত: (2011)
• KS900: a hypoxia-directed, reductively activated methylating antitumor prodrug that selectively ablates O(6)-alkylguanine-DNA alkyltransferase in neoplastic cells
  অনুযায়ী: Baumann, Raymond P., অন্যান্য
  প্রকাশিত: (2011)
• Development of an O(6)-alkylguanine—DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-(3)H]O(6)-benzylguanine to the protein
  অনুযায়ী: Ishiguro, Kimiko, অন্যান্য
  প্রকাশিত: (2008)
• A strategy for selective O(6)-alkylguanine-DNA alkyltransferase depletion under hypoxic conditions
  অনুযায়ী: Penketh, Philip G., অন্যান্য
  প্রকাশিত: (2012)