Загрузка...
Structure of an apoptosome-procaspase-9 CARD complex
Apaf-1 co-assembles with cytochrome c to form the apoptosome, which then binds and activates procaspase-9. We removed pc-9 catalytic domains from the holo-apoptosome by site-directed thrombinolysis. A structure of the resulting apoptosome-pc-9 CARD complex was then determined at ~9.5Å resolution. In...
Сохранить в:
| Главные авторы: | , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874686/ https://ncbi.nlm.nih.gov/pubmed/20462491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.04.001 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|