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The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3

Activation of procaspase-9 on the apoptosome is a pivotal step in the intrinsic cell death pathway. We now provide further evidence that caspase recruitment domains of pc-9 and Apaf-1 form a CARD-CARD disk that is flexibly-tethered to the apoptosome. In addition, a 3D reconstruction of the pc-9 apop...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yuan, Shujun, Yu, Xinchao, Asara, John M., Heuser, John E., Ludtke, Steven J., Akey, Christopher W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155825/
https://ncbi.nlm.nih.gov/pubmed/21827945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.07.001
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