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cIAP1 Cooperatively Inhibits Procaspase-3 Activation by the Caspase-9 Apoptosome
Although early studies of inhibitor of apoptosis proteins (IAPs) suggested that cIAP1 directly binds and inhibits caspases similarly to X-linked IAP (XIAP), a recent one found that micromolar concentrations of cIAP1 only weakly inhibit caspase-3, -7, or -9. Here, we show that cIAP1 specifically and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943263/ https://ncbi.nlm.nih.gov/pubmed/20667824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125955 |
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