Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability

Lignende værker

• Variants of human thymidylate synthase with loop 181–197 stabilized in the inactive conformation
  af: Lovelace, Leslie L, et al.
  Udgivet: (2009)
• Cooperative Inhibition of Human Thymidylate Synthase by Mixtures of Active Site Binding and Allosteric Inhibitors
  af: Lovelace, Leslie L., et al.
  Udgivet: (2007)
• The R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195
  af: Gibson, Lydia M., et al.
  Udgivet: (2008)
• Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding
  af: Gibson, Lydia M., et al.
  Udgivet: (2011)
• Role of N-terminal residues in the ubiquitin-independent degradation of human thymidylate synthase
  af: Peña, Maria Marjorette O., et al.
  Udgivet: (2006)