Cooperative Inhibition of Human Thymidylate Synthase by Mixtures of Active Site Binding and Allosteric Inhibitors

Por Lovelace, Leslie L., Gibson, Lydia M., Lebioda, Lukasz
Publicado em 2007

The R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195

Por Gibson, Lydia M., Lovelace, Leslie L., Lebioda, Lukasz
Publicado em 2008

Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding

Por Gibson, Lydia M., Celeste, Lesa R., Lovelace, Leslie L., Lebioda, Lukasz
Publicado em 2011

Structure of Human C8 Protein Provides Mechanistic Insight into Membrane Pore Formation by Complement

Por Lovelace, Leslie L., Cooper, Christopher L., Sodetz, James M., Lebioda, Lukasz
Publicado em 2011

The Structures of Thiolate- and Carboxylate-Ligated Ferric H93G Myoglobin: Models for Cytochrome P450 and for Oxyanion-Bound Heme Proteins

Por Qin, Jie, Perera, Roshan, Lovelace, Leslie L., Dawson, John H., Lebioda, Lukasz
Publicado em 2006

Fluoride Inhibition of Enolase: Crystal Structure and Thermodynamics

Por Qin, Jie, Chai, Geqing, Brewer, John M., Lovelace, Leslie L., Lebioda, Lukasz
Publicado em 2006

Structures of Asymmetric Complexes of Human Neuron Specific Enolase with Resolved Substrate and Product and an Analogous Complex with Two Inhibitors Indicate Subunits Interaction a...

Por Qin, Jie, Chai, Geqing, Brewer, John M., Lovelace, Leslie L., Lebioda, Lukasz
Publicado em 2012

Mechanism of N(10)-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors

Por Celeste, Lesa R, Chai, Geqing, Bielak, Magdalena, Minor, Wladek, Lovelace, Leslie L, Lebioda, Lukasz
Publicado em 2012

Crystal Structure of the MACPF Domain of Human Complement Protein C8α in Complex with the C8γ Subunit

Por Slade, Daniel J., Lovelace, Leslie L., Chruszcz, Maksymilian, Minor, Wladek, Lebioda, Lukasz, Sodetz, James M.
Publicado em 2008

Variants of human thymidylate synthase with loop 181–197 stabilized in the inactive conformation

Por Lovelace, Leslie L, Johnson, Saphronia R, Gibson, Lydia M, Bell, Brittnaie J, Berger, Sondra H, Lebioda, Lukasz
Publicado em 2009

Complex of myoglobin with phenol bound in a proximal cavity

Por Huang, Xiao, Wang, Chunxue, Celeste, Lesa R., Lovelace, Leslie L., Sun, Shenfang, Dawson, John H., Lebioda, Lukasz
Publicado em 2012

Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability

Por Huang, Xiao, Gibson, Lydia M., Bell, Brittnaie J., Lovelace, Leslie L., Peña, Maria Marjorette O., Berger, Franklin G., Berger, Sondra H., Lebioda, Lukasz
Publicado em 2010