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Fluoride Inhibition of Enolase: Crystal Structure and Thermodynamics

Enolase is a dimeric metal-activated metalloenzyme, which uses two magnesium ions per subunit: the strongly bound conformational ion and the catalytic ion that binds to the enzyme-substrate complex inducing catalysis. The crystal structure of the human neuronal enolase-Mg2F2P(i) complex (enolase flu...

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Autors principals: Qin, Jie, Chai, Geqing, Brewer, John M., Lovelace, Leslie L., Lebioda, Lukasz
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566932/
https://ncbi.nlm.nih.gov/pubmed/16411755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051558s
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