Llwytho...

Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability

Human and other mammalian thymidylate synthase (TS) enzymes have an N-terminal extension of about 27 amino acids which is not present in bacterial TSs. The extension, which is disordered in all reported crystal structures of TSs, has been considered to play a primary role in protein turnover but not...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Huang, Xiao, Gibson, Lydia M., Bell, Brittnaie J., Lovelace, Leslie L., Peña, Maria Marjorette O., Berger, Franklin G., Berger, Sondra H., Lebioda, Lukasz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856444/
https://ncbi.nlm.nih.gov/pubmed/20151707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901457e
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!