Caricamento...

Functionalized 2′-Amino-α-L-LNA - Directed Positioning of Intercalators for DNA Targeting

Chemically modified oligonucleotides are increasingly applied in nucleic acid based therapeutics and diagnostics. LNA (Locked Nucleic Acid) and its diastereomer α-L-LNA are two promising examples hereof that exhibit increased thermal and enzymatic stability. Herein, the synthesis, biophysical charac...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kumar, T. Santhosh, Madsen, Andreas S., Østergaard, Michael E., Sau, Sujay P., Wengel, Jesper, Hrdlicka, Patrick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853939/
https://ncbi.nlm.nih.gov/pubmed/19108636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo802037v
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !