Methylation pattern of the O(6)-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis

O(6)-methylguanine-DNA methyltransferase (MGMT) is a DNA repair gene which is frequently methylated in colorectal cancer (CRC). However, it remains controversial whether methylation of specific CpG sequences within MGMT promoter leads to loss of its protein expression, and if MGMT methylation correl...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nagasaka, Takeshi, Goel, Ajay, Notohara, Kenji, Takahata, Takaomi, Sasamoto, Hiromi, Uchida, Takuyuki, Nishida, Naoshi, Tanaka, Noriaki, Boland, Clement Richard, Matsubara, Nagahide
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851179/
https://ncbi.nlm.nih.gov/pubmed/18240147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23398
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky