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Aberrant Methylation of Multiple Tumor Suppressor Genes in Aging Liver, Chronic Hepatitis, and Hepatocellular Carcinoma

Aberrant DNA methylation is an important epigenetic alteration in hepatocellular carcinoma (HCC). However, the molecular processes underlying the methylator phenotype and the contribution of hepatitis viruses are poorly understood. The current study is a comprehensive methylation analysis of human l...

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Main Authors: Nishida, Naoshi, Nagasaka, Takeshi, Nishimura, Takafumi, Ikai, Iwao, Boland, C. Richard, Goel, Ajay
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865182/
https://ncbi.nlm.nih.gov/pubmed/18161048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22110
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