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Aberrant Methylation of Multiple Tumor Suppressor Genes in Aging Liver, Chronic Hepatitis, and Hepatocellular Carcinoma

Aberrant DNA methylation is an important epigenetic alteration in hepatocellular carcinoma (HCC). However, the molecular processes underlying the methylator phenotype and the contribution of hepatitis viruses are poorly understood. The current study is a comprehensive methylation analysis of human l...

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Hlavní autoři: Nishida, Naoshi, Nagasaka, Takeshi, Nishimura, Takafumi, Ikai, Iwao, Boland, C. Richard, Goel, Ajay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865182/
https://ncbi.nlm.nih.gov/pubmed/18161048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22110
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