Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the most fatal human malignancies, but the molecular mechanisms of hepatocarcinogenesis remain unclear. Although p53 mutations are frequently observed in Asian HCC, it is not a common event in Western HCC. Recent studies suggest that tumor suppressor genes (T...

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Главные авторы: Yang, Bin, Guo, Mingzhou, Herman, James G., Clark, Douglas P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2003
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Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868243/
https://ncbi.nlm.nih.gov/pubmed/12937151
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