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Aberrant DNA methylation in hepatocellular carcinoma tumor suppression (Review)
Aberrant DNA methylation leads to altered gene expression, resulting in cancerous features. Numerous tumor suppressor genes are silenced by DNA methylation during hepatocarcinogenesis. Promoter CpG island hypermethylation is an important mechanism for inactivating tumor suppressor genes in hepatocel...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114628/ https://ncbi.nlm.nih.gov/pubmed/25120642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2301 |
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