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Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the most fatal human malignancies, but the molecular mechanisms of hepatocarcinogenesis remain unclear. Although p53 mutations are frequently observed in Asian HCC, it is not a common event in Western HCC. Recent studies suggest that tumor suppressor genes (T...

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Bibliografiske detaljer
Main Authors: Yang, Bin, Guo, Mingzhou, Herman, James G., Clark, Douglas P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868243/
https://ncbi.nlm.nih.gov/pubmed/12937151
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