Analysis of Fecal DNA Methylation to Detect Gastrointestinal Neoplasia

BACKGROUND: The development of noninvasive screening tests is important to reduce mortality from gastrointestinal neoplasia. We sought to develop such a test by analysis of DNA methylation from exfoliated cancer cells in feces. METHODS: We first analyzed methylation of the RASSF2 and SFRP2 gene prom...

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Hauptverfasser: Nagasaka, Takeshi, Tanaka, Noriaki, Cullings, Harry M., Sun, Dong-Sheng, Sasamoto, Hiromi, Uchida, Takuyuki, Koi, Minoru, Nishida, Naoshi, Naomoto, Yoshio, Boland, C. Richard, Matsubara, Nagahide, Goel, Ajay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762745/
https://ncbi.nlm.nih.gov/pubmed/19700653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp265
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