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Methylation pattern of the O(6)-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis
O(6)-methylguanine-DNA methyltransferase (MGMT) is a DNA repair gene which is frequently methylated in colorectal cancer (CRC). However, it remains controversial whether methylation of specific CpG sequences within MGMT promoter leads to loss of its protein expression, and if MGMT methylation correl...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851179/ https://ncbi.nlm.nih.gov/pubmed/18240147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23398 |
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