載入...

O(6)-Methylguanine-DNA methyltransferase deficiency in developing brain: Implications for brain tumorigenesis

The DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT) is a cardinal defense against the mutagenic and carcinogenic effects of alkylating agents. We have reported evidence that absence of detectable MGMT activity (MGMT(−) phenotype) in human brain is a predisposing factor for primary...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Bobola, Michael S., Blank, A., Berger, Mitchel S., Silber, John R.
格式: Artigo
語言:Inglês
出版: 2007
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692685/
https://ncbi.nlm.nih.gov/pubmed/17500046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.03.009
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!