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O(6)-methylguanine-DNA methyltransferase in glioma therapy: Promise and problems
Gliomas are the most frequent adult primary brain tumor, and are invariably fatal. The most common diagnosis glioblastoma (GBM) afflicts 12,500 new patents in the U.S. annually, and has a median survival of approximately one year when treated with the current standard of care. Alkylating agents have...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340514/ https://ncbi.nlm.nih.gov/pubmed/22244911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2011.12.004 |
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