טוען...
Conformational States of Human Purine Nucleoside Phosphorylase at Rest, at Work and with Transition State Analogues
Human purine nucleoside phosphorylase (PNP) is a homotrimer binding tightly to the transition state analogues Immucillin-H (ImmH, K(d) = 56 pM) and DATMe-ImmH-Immucillin-H (DATMe-ImmH, K(d) = 8.6 pM). ImmH binds with a larger entropic penalty than DATMe-ImmH, a chemically more flexible inhibitor. Th...
שמור ב:
| Main Authors: | , , , , , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832846/ https://ncbi.nlm.nih.gov/pubmed/20108972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902041j |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|