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Converse modulation of toxic α-synuclein oligomers in living cells by N′-benzylidene-benzohydrazide derivates and ferric iron

Intracellular α-synuclein (α-syn) aggregates are the pathological hallmark in several neurodegenerative diseases including Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. Recent evidence suggests that small oligomeric aggregates rather than large amyloid fibrils repr...

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Bibliografiske detaljer
Main Authors: Hillmer, Andreas S., Putcha, Preeti, Levin, Johannes, Högen, Tobias, Hyman, Bradley T., Kretzschmar, Hans, McLean, Pamela J., Giese, Armin
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812586/
https://ncbi.nlm.nih.gov/pubmed/19914207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.11.080
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