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Converse modulation of toxic α-synuclein oligomers in living cells by N′-benzylidene-benzohydrazide derivates and ferric iron

Intracellular α-synuclein (α-syn) aggregates are the pathological hallmark in several neurodegenerative diseases including Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. Recent evidence suggests that small oligomeric aggregates rather than large amyloid fibrils repr...

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Detalhes bibliográficos
Main Authors: Hillmer, Andreas S., Putcha, Preeti, Levin, Johannes, Högen, Tobias, Hyman, Bradley T., Kretzschmar, Hans, McLean, Pamela J., Giese, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812586/
https://ncbi.nlm.nih.gov/pubmed/19914207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.11.080
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