Modelling Ser129 Phosphorylation Inhibits Membrane Binding of Pore-Forming Alpha-Synuclein Oligomers

BACKGROUND: In several neurodegenerative diseases, hyperphosphorylation at position Ser129 is found in fibrillar deposits of alpha-synuclein (asyn), implying a pathophysiological role of asyn phosphorylation in neurodegeneration. However, recent animal models applying asyn phosphorylation mimics dem...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Nübling, Georg Sebastian, Levin, Johannes, Bader, Benedikt, Lorenzl, Stefan, Hillmer, Andreas, Högen, Tobias, Kamp, Frits, Giese, Armin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049638/
https://ncbi.nlm.nih.gov/pubmed/24911099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098906
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares