Normal polymorphic variations and transcription of the decay accelerating factor gene in paroxysmal nocturnal hemoglobinuria cells.

In paroxysmal nocturnal hemoglobinuria (PNH), an acquired hemolytic anemia, deficiency of decay accelerating factor (DAF) renders blood cells susceptible to increased deposition of autologous complement activation fragments (C3b) and complemented-mediated injury. To investigate the mechanism of the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Stafford, H A, Tykocinski, M L, Lublin, D M, Holers, V M, Rosse, W F, Atkinson, J P, Medof, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.3.880
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