Synthesis of aberrant decay-accelerating factor proteins by affected paroxysmal nocturnal hemoglobinuria leukocytes.

Paroxysmal nocturnal hemoglobinuria (PNH) leukocytes fail to express decay-accelerating factor (DAF) but contain DAF mRNA transcripts resembling those in normal cells. To further investigate the nature of the DAF defect in affected cells, patients' polymorphonuclear and mononuclear leukocytes (...

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Vydáno v:J Clin Invest
Hlavní autoři: Carothers, D J, Hazra, S V, Andreson, S W, Medof, M E
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1990
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296385/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688570/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114432
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