Synthesis of aberrant decay-accelerating factor proteins by affected paroxysmal nocturnal hemoglobinuria leukocytes.

Paroxysmal nocturnal hemoglobinuria (PNH) leukocytes fail to express decay-accelerating factor (DAF) but contain DAF mRNA transcripts resembling those in normal cells. To further investigate the nature of the DAF defect in affected cells, patients' polymorphonuclear and mononuclear leukocytes (PMN a...

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Publié dans:	J Clin Invest
Auteurs principaux:	Carothers, D J, Hazra, S V, Andreson, S W, Medof, M E
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296385/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114432
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