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Paroxysmal nocturnal hemoglobinuria and thrombosis

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired clonal hematopoiesis disorder caused by a somatic mutation in the PIGA (phosphatidylinositol glycan, class A) gene, resulting in deficiency of glycosylphosphatidylinositol (GPI)anchored complement regulatory proteins on blood cell surface....

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Auteurs principaux: A. R. Khisamieva, A. R. Oskolkova, V. O. Bitsadze, J. Kh. Khizroeva, N. A. Makatsariya, M. V. Tretyakova, N. R. Gashimova, K. N. Grigoreva, D. V. Blinov, J.-Ch. Gris, I. Elalamy, G. Gerotziafas, A. D. Makatsariya
Format: Artigo
Langue:Russo
Publié: IRBIS LLC 2026-03-01
Collection:Акушерство, гинекология и репродукция
Sujets:
paroxysmal nocturnal hemoglobinuria
pnh
complement system
thromboses
pregnancy
obstetric risk
Accès en ligne:https://www.gynecology.su/jour/article/view/2712
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