Synthesis of aberrant decay-accelerating factor proteins by affected paroxysmal nocturnal hemoglobinuria leukocytes.

Paroxysmal nocturnal hemoglobinuria (PNH) leukocytes fail to express decay-accelerating factor (DAF) but contain DAF mRNA transcripts resembling those in normal cells. To further investigate the nature of the DAF defect in affected cells, patients' polymorphonuclear and mononuclear leukocytes (PMN a...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Carothers, D J, Hazra, S V, Andreson, S W, Medof, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296385/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114432
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