Normal polymorphic variations and transcription of the decay accelerating factor gene in paroxysmal nocturnal hemoglobinuria cells.

In paroxysmal nocturnal hemoglobinuria (PNH), an acquired hemolytic anemia, deficiency of decay accelerating factor (DAF) renders blood cells susceptible to increased deposition of autologous complement activation fragments (C3b) and complemented-mediated injury. To investigate the mechanism of the...

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Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Stafford, H A, Tykocinski, M L, Lublin, D M, Holers, V M, Rosse, W F, Atkinson, J P, Medof, M E
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1988
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.3.880
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