Normal polymorphic variations and transcription of the decay accelerating factor gene in paroxysmal nocturnal hemoglobinuria cells.

In paroxysmal nocturnal hemoglobinuria (PNH), an acquired hemolytic anemia, deficiency of decay accelerating factor (DAF) renders blood cells susceptible to increased deposition of autologous complement activation fragments (C3b) and complemented-mediated injury. To investigate the mechanism of the...

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出版年:	Proc Natl Acad Sci U S A
主要な著者:	Stafford, H A, Tykocinski, M L, Lublin, D M, Holers, V M, Rosse, W F, Atkinson, J P, Medof, M E
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 1988
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.3.880
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