Normal polymorphic variations and transcription of the decay accelerating factor gene in paroxysmal nocturnal hemoglobinuria cells.

In paroxysmal nocturnal hemoglobinuria (PNH), an acquired hemolytic anemia, deficiency of decay accelerating factor (DAF) renders blood cells susceptible to increased deposition of autologous complement activation fragments (C3b) and complemented-mediated injury. To investigate the mechanism of the...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Stafford, H A, Tykocinski, M L, Lublin, D M, Holers, V M, Rosse, W F, Atkinson, J P, Medof, M E
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1988
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.3.880
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