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Amelioration of lytic abnormalities of paroxysmal nocturnal hemoglobinuria with decay-accelerating factor.

Purified decay-accelerating factor (DAF), from the stroma of normal human erythrocytes, was incorporated into the membranes of erythrocytes of patients with paroxysmal nocturnal hemoglobinuria (PNH), and its effect on the complement sensitivity of the cells was investigated. Reconstitution with exog...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Medof, M E, Kinoshita, T, Silber, R, Nussenzweig, V
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2581259/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.9.2980
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