Affected erythrocytes of patients with paroxysmal nocturnal hemoglobinuria are deficient in the complement regulatory protein, decay accelerating factor.

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired defect of bone marrow stem cells in which the affected clones produce erythrocytes (also granulocytes and platelets) with membranes that are abnormally sensitive to complement-mediated lysis. Abnormal erythrocytes (E) from patients with PNH (P...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Nicholson-Weller, A, March, J P, Rosenfeld, S I, Austen, K F
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1983
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6576376/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.16.5066
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